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http://www.rxlist.com/cgi/generic/benzaclin_wcp.htm This is what nearly every physician prescribes for acne nowadays and NONE ever mention that this procedure provides CANCER! I've been by using this for nearly annually now... Every single day! " Carcinogenesis, Mutagenesis, Impairment of Fertility: Benzoyl peroxide has been proven to be always a tumor promoter and development representative in numerous animal studies. The clinical need for this really is unknown. Benzoyl peroxide in acetone at doses of 5 and 10 mg given twice each week induced skin tumors in transgenic Tg.AC rats in research using 20 months of external therapy. In a week dermal photocarcinogenicity research in hairless rats, the median time for you to onset of skin tumor formation was reduced and the amount of tumors per mouse improved following chronic concurrent external administration of BenzaClin Topical Gel with coverage to ultraviolet radiation (40 weeks of therapy followed closely by 12 weeks of observation). Genotoxicity reports weren't performed with BenzaClin Topical Gel. Clindamycin phosphate wasn't genotoxic in Salmonella typhimurium or in a rat micronucleus test. Clindamycin phosphate sulfoxide, an degradation product of benzoyl peroxide and clindamycin phosphate, wasn't clastogenic in a mouse micronucleus test. Benzoyl peroxide has been observed to cause DNA strand breaks in a number of mammalian cell forms, to be mutagenic in S. typhimurium assessments by some although not all researchers, and to trigger sister chromatid exchanges in Chinese hamster ovary cells. Reports haven't been done with BenzaClin Topical Gel or benzoyl peroxide to judge the result on fertility. On fertility or mating ability" no effects were revealed by fertility studies in rats treated orally with up to 300 mg/kg/day of clindamycin ( approximately 120 times the amount of clindamycin in the highest recommended adult human dose of 2.5 g BenzaClin Topical Gel, based on mg/m2 ).
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